North Bengal Medical College was originally envisioned by Dr. Bidhan Chandra Roy, Ex-Chief Minister of West Bengal. North Bengal University Medical College (NBUMC), now known as North Bengal Medical College (NBMC) came up on paper (not on ground) by the act of an advertisement in the Anandabazar Patrika in August 1967 for admission to first Premedical course of this institute by North Bengal University (NBU). Premedical course was abolished after 1976.

First batch of students for premedical course was admitted as per merit list of Higher Secondary examination. Class for 1st batch consisting of 46 boys and 6 girls was started on 6.11.67 on makeshift arrangement at Jackson medical school, Jalpaiguri. Students at that time were accommodated at Jalpaiguri Polytechnic School.